Skip to main content

Table 5 Echocardiographic and demographic parameters of the Morquio A cohort indicating high prevalence of mitral and aortic valve pathology, as well as aortic root dilatation. Aortic root Z-scores that indicate aortic root dilatation are highlighted in bold. n.a.; not analyzed

From: Abnormally increased carotid intima media-thickness and elasticity in patients with Morquio A disease

Patient

Mitral Valve

Aortic Valve

LV Size / Function

Aortic Root Z-Score

Anatomy

Function

Anatomy

Function

1

Mildly Thickened

Normal

Normal

Normal

Normal

n.a.

2

Mildly Thickened

Normal

Mildly Thickened

Normal

Normal

n.a.

3

Normal

Normal

Normal

Normal

Normal

+ā€‰1.11

4

Mildly Thickened

Normal

Mildly Thickened

Normal

Normal

+ā€‰2.41

5

n.a.

n.a.

n.a.

n.a.

n.a.

n.a.

6

Thickened

Trivial Regurgitation

Thickened

Normal

Normal

+ā€‰3.28

7

Mild Dysplasia

Trivial Regurgitation

Thickened

Trivial Regurgitation

Normal

+ā€‰1.97

8

Thickened

Normal

Thickened

Normal

Normal

+ā€‰1.06

9

Mildly Thickened

Normal

Mildly Thickened

Normal

Normal

+ā€‰4.62

10

Normal

Normal

Cusp Asymmetry

Moderate Regurgitation

Mild dilatation

+ā€‰4.92

11

Minimally Thickened

Normal

Minimally Thickened

Normal

Normal

+ā€‰0.43

12

Normal

Normal

Slightly Thickened

Trivial Regurgitation

Normal

+ā€‰2.43

Ā 

73% Thickened

18% Regurgitation

82% Abnormal

27% Regurgitation

9% LV Dilatation

56% with Dilatation

27% Normal

82% Normal

18% Normal

73% Normal

91% Normal

44% Normal