Abnormally increased carotid intima media-thickness and elasticity in patients with Morquio A disease

Table 3 Ratio comparisons between mean carotid measures of Morquio A patients, non-Morquio MPS patients (“Other MPS”), and pediatric control groups adjusted for sex, age, and height

Vascular Measure	Covariate	Ratio (95% CI)	P-value
	Control vs. Morquio A	0.80 (0.76, 0.84)	*< 0.001*
	Other MPS vs. Morquio A	1.00 (0.95, 1.05)	0.956
cIMT (mm)	Female (vs. Male)	0.98 (0.97, 1.00)	*0.038*
	Age (per 10 yr)	1.03 (0.99, 1.06)	0.114
	Height (per 10 cm)	1.00 (0.99, 1.01)	0.931
	Control vs. Morquio A	1.07 (0.88, 1.30)	0.521
	Other MPS vs. Morquio A	1.02 (0.80, 1.30)	0.875
cCSD (%)	Female (vs. Male)	1.01 (0.97, 1.05)	0.668
	Age (per 10 yr)	0.71 (0.64, 0.79)	*< 0.001*
	Height (per 10 cm)	1.04 (1.02, 1.06)	*< 0.001*
	Control vs. Morquio A	0.70 (0.57, 0.87)	*< 0.001*
cCSC1	Other MPS vs. Morquio A	0.61 (0.47, 0.79)	*< 0.001*
(mm² · mm Hg⁻¹)	Female (vs. Male)	0.95 (0.90, 1.00)	*0.045*
	Age (per 10 yr)	0.83 (0.74, 0.93)	*0.001*
	Height (per 10 cm)	1.01 (0.98, 1.04)	0.502
	Control vs. Morquio A	1.50 (1.15, 1.96)	*0.003*
	Other MPS vs. Morquio A	2.18 (1.63, 2.92)	*< 0.001*
cIEM (mm Hg)	Female (vs. Male)	0.95 (0.90, 1.01)	0.121
	Age (per 10 yr)	1.48 (1.30, 1.70)	*< 0.001*
	Height (per 10 cm)	0.99 (0.95, 1.02)	0.364

Ratios less than 1.00 indicate the first comparator is less than the second comparator; ratios greater than 1.00 indicate the first comparator is greater than the second comparator. Significant comparisons are highlighted in bold

ISSN: 1750-1172