Table 3 Results of the logistic regression model adjusted for possible confounders (age, sex and BMI) showing the association between the clinical features and genetic status
From: Can we identify individuals with an ALPL variant in adults with persistent hypophosphatasaemia?
Clinical feature | Odds Ratio | 95% IC | p value |
|---|---|---|---|
Musculoskeletal pain | 7.6 | 1.9–30.9 | 0.005** |
Peripheral fractures | 1.2 | 0.4–4 | 0.769 |
Family history of fractures | 0.4 | 0.06–2.2 | 0.273 |
Orthopedic surgery | 3.7 | 0.5–27.1 | 0.199 |
History of premature tooth loss | 1.7 | 0.1–21.9 | 0.673 |
Dental abnormalities | 3.6 | 0.9–13.4 | 0.053 |
Family history of dental problems | 0.7 | 0.2–2.3 | 0.513 |
Muscle weakness | 3.1 | 0.4–27.6 | 0.309 |
Calcific periarthritis | 1.5 | 0.2–9.9 | 0.680 |