HPO Term | GPI-anchored genes | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
APLI | ALPL | ALPP | ALPPL2 | CNTN1 | FOLR1 | GPC6 | GPC3 | CD59 | CNTN2 | GPIHBP1 | CD55 | |
Hyperphosphatasia | x | x | x | x | Â | Â | Â | Â | Â | Â | Â | Â |
High palate | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | Â |
Hypertelorism | Â | Â | Â | Â | x | Â | Â | x | Â | Â | Â | Â |
Muscular hypotonia | Â | Â | Â | Â | x | Â | Â | x | x | Â | Â | Â |
Generalized hypotonia | Â | Â | Â | Â | Â | Â | Â | x | x | Â | Â | Â |
Polyhydramnios | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | Â |
Feeding difficulties | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | Â |
Camptodactyly | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | Â |
Intellectual disability | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â |
Seizures | Â | Â | Â | Â | Â | x | Â | Â | Â | x | Â | Â |
Malar flattening | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â |
Epicanthus | Â | Â | Â | Â | Â | Â | x | x | Â | Â | Â | Â |
Micrognathia | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â |
Depressed nasal bridge | Â | Â | Â | Â | Â | Â | x | x | Â | Â | Â | Â |
Wide nasal bridge | Â | Â | Â | Â | Â | Â | x | x | Â | Â | Â | Â |
Short neck | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â |
Atrial septal defect | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â |
Frontal bossing | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â |
Short nose | Â | Â | Â | Â | Â | Â | x | x | Â | Â | Â | Â |
Tremor | Â | Â | Â | Â | Â | Â | Â | Â | Â | x | Â | Â |
Cleft palate | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Coarse facial features | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Hepatomegaly | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | x | x |
Macrocephaly | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Patent ductus arteriosus | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Short distal phalanx of finger | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Small nail | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Splenomegaly | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | x | Â |
Anteverted nares | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Wide mouth | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Splenomegaly | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â |
Failure to thrive | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | x | Â |
Growth delay | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | x |