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Table 2 Genes in the GPI biosynthetic pathway anchoring process, Transamidase+Remodeling stage. Abbreviations as in Table 1

From: Significantly different clinical phenotypes associated with mutations in synthesis and transamidase+remodeling glycosylphosphatidylinositol (GPI)-anchor biosynthesis genes

Gene name (Entrez ID)# Patients curatedDisease AssociationInheritance
GPAA1 (8733)10OMIM:617810 GPI biosynthesis defect 15AR
MPPE1 (65258)0n/a 
PGAP1 (80055)7OMIM: 615802 Mental retardation, autosomal recessive 42AR
PGAP2 (27315)10OMIM: 614207 HPMRS 3AR
PGAP3 (93210)22OMIM:615716 HPMRS 4AR
PIGK (10026)0n/a 
PIGS (94005)0OMIM:618143 GPI biosynthesis defect-18AR
PIGT (51604)10OMIM:615399, Paroxysmal nocturnal hemoglobinuria 2, (PNH 2); MIM: 615398 MCAHS 3AD/AR
PIGU (128869)0n/a