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Table 3 Neurological characteristics of Glu54Gln-mutated ATTR

From: Clinical characteristics in patients with hereditary amyloidosis with Glu54Gln transthyretin identified in the Romanian population

Neurological characteristics at diagnosis for symptomatic patientsGlu54Gln ATTR
NIS-LL, mean, range (N = 8)13.4 [4–26]
mBMI, (g/l) x (kg/m2), mean, range (N = 8)1084 [611–1444]
PND scale (8 patients)Grade I, n (%)5 (63%)
Grade II, n (%)3 (37%)
Polyneuropathy, n (%) (N = 13)12 (92%)
Carpal tunnel syndrome, n (%) (N = 13)7 (53%)
Orthostatic hypotension, n (%) (N = 13)9 (69%)
Diarrhea, n (%) (N = 13)4 (31%)
Constipation, n (%) (N = 13)5 (38%)
Weight loss, n (%) (N = 13)8 (62%)
  1. mBMI modified body mass index, NIS-LL neuropathy impairment score of lower limbs, PND polyneuropathy disability score