Patient [family] | Age at diagnosis | Diagnosis (year) | Mean time from diagnosis to onset (months) | Symptoms at onset | Peripheral nervous system dysfunction | Autonomic dysfunction | Cardiac features | Alive/deceased |
---|---|---|---|---|---|---|---|---|
1 [A] | 48 | 2005 | 36 | CTS Paresthesia | SM-PN CTS | OHT Dysphagia Diarrhea | HF | Deceased |
2 [B] | 43 | 2008 | 36 | CTS | CTS | – | HF | Deceased |
3 [C1*] | 35 | 2012 | 11 | HF Weight loss Paresthesia | Paresthesia | Diarrhea OHT | HF 1st degree AV block | Deceased |
4 (C2*) | 49 | 2017 | 24 | Paresthesia Weight loss | SM-PN | OHT Constipation | HF 1st degree AV block SVES RBBB pericardial effusion | Alive |
5 [D] | 51 | 2016 | 48 | Diarrhea Weight loss | SM-PN | Diarrhea OHT | HF AF | Alive |
6 [E1*] | 52 | 2017 | 9 | Paresthesia Weight loss | SM-PN CTS | Constipation OHT | HF RBBB | Alive |
7 [E2*] | 47 | 2017 | 24 | Paresthesia Weight loss | SM-PN | Constipation OHT | – | Alive |
8[E3**] | 47 | 2017 | 7 | Paresthesia | SM-PN CTS | – | SVES | Alive |
9 [F] | 49 | 2017 | 36 | Paresthesia | SM-PN CTS | – | HF 1st degree AV block AF | Alive |
10 [G] | 49 | 2017 | 60 | Paresthesia | SM-PN CTS | Constipation | HF Trifascicular block Pericardial effusion | Alive |
11 [H] | 42 | 2018 | 6 | Weight loss Gastroparesis | S-PN CTS | OHT Gastroparesis Diarrhea/constipation | HF 3rd degree AV block NSVT RBBB | Alive |
12 [I1*] | 41 | 2017 | 48 | Paresthesia CTS Weight loss | SM-PN | Constipation OHT Urinary dysfunction | HF RBBB | Alive |
13 [I2*] | 46 | 2017 | 60 | Paresthesia Weight loss | SM-PN | OHT | HF | Alive |