Depressive symptoms in Fabry disease: the importance of coping, subjective health perception and pain

Table 3 Summary of multiple linear regression Model 1 and 2

Model 1					Model 2
Independent variables	B (95% CI)	SE B	β	p-value	B (95% CI)	SE B	β	p-value
BPI severity	1.60 (0.63–2.58)	0.49	0.35	0.002	0.82 (0.04–1.59)	0.39	0.18	0.039
Unfit for work	0.23 (−5.22–5.69)	2.74		0.933	0.47 (−3.57–4.51)	2.03		0.817
SF-36 Health perception	−0.19 (−0.30 – −0.09)	0.05	− 0.41	< 0.001	− 0.13 (− 0.21 – − 0.05)	0.04	−0.28	0.001
Single	−0.49 (−4.42–3.43)	1.97		0.804	− 0.60 (− 3.55–2.35)	1.48		0.687
Comorbidity	−6.15 (−10.20 – −2.10)	2.03		0.003	−2.92 (− 6.07–0.23)	1.58		0.069
Stroke	3.18 (− 3.02–9.39)	3.11		0.309	3.18 (− 1.41–7.77)	2.30		0.171
Avoidance and brooding					5.39 (3.82–6.95)	0.79	0.50	< 0.0001
Positivity and problem solving					−3.12 (−4.53 – −1.71)	0.71	−0.29	< 0.0001
Seeking social support and comfort					−0.14 (−1.56–1.29)	0.72	−0.01	0.849
Intercept	20.74				18.14
F-value	9.43			< 0.0001	18.68			< 0.0001
R²	43.3% (24.3–53.7)				70.3% (53.9–75.9)
Adjusted R²	39.3%				67.1%

B beta coefficients, β standardized beta coefficients for continuous variables, SE standard Error, BPI Brief Pain Inventory, SF-36 Short Form-36 Health Survey

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