From: Perinatal features of Prader-Willi syndrome: a Chinese cohort of 134 patients
Perinatal variables | China (N = 134) | France (N = 86) (2006)[11] | United Kingdom (N = 46) (2008)[12] | France (N = 61) (2017)[5] | United States (N = 64) (2018)[13] | United States (N = 355) (2018)[14] |
---|---|---|---|---|---|---|
Mean maternal age (year): Deletion | 29.6 | 29.3 | 31.4 | 31 | 28.7 | 29.2 |
UPD | 36.0 | 36.4 | 37.9 | 38 | 36.7 | 35.2 |
Decreased fetal movements | 109/124 (87.9%) | 47.6% | 67.4% | 27% | 85.6% | 78% |
Polyhydramnios | 57 (42.6%) | 26.7%* | 28.3% | 23.0%* | NA | 18%** |
Vaginal delivery | 23 (17.2%) | 41.8% | 17.4% | 32.7% | 56.5% | 45.4% |
Caesarean section | 111 (82.8%) | 53.4% | 52.2% | 67% | 42.1% | 54.6% |
Preterm < 37 weeks | 22 (16.4%) | 15% | 37% | 20% | 31.7% | 26% |
Hypotonia | 132 (98.5%) | 96.5% | 100% | NA | 84.3% | 99.7% |
Feeding difficulty | 133 (99.3%) | 82.5% | 100% | 84.4% | 96.8% | 99% |