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Table 2 Hemoglobin electrophoresis information of the study participants categorized based on MCV and MCH parameters

From: Nationwide carrier detection and molecular characterization of β-thalassemia and hemoglobin E variants in Bangladeshi population

GroupsNo. of participants, n (%) Total, N = 1877Hb electrophoresis results
BTT suspects, n (%) (HbA2 > 3.5%)ETT Suspects, n (%) (HbE = 25–30%)HbE disease, n (%) (HbE > 90%HbA = 0%)Others Hb Variants, n (%)Total participants with abnormal Hb-electrophoresis, n (%)Normal Hb electrophoresis results, n (%)
Group A
(MCV ≥ 80 fL and MCH ≥ 27 pg)
995 (53.0)3 (0.3)2 (0.2)04 (0.4)9 (0.9)986 (99.1)
Group B
(MCV < 80 fL and MCH < 27 pg)
612 (32.6)41 (6.6)161 (26.3)8 (1.3)5 (0.8)215 (35.0)397 (65.0)
Group C
(MCV < 80 fL and MCH ≥ 27 pg)
13 (0.7)0000013 (100.0)
Group D
(MCV ≥ 80 fL and MCH < 27 pg)
257 (13.7)2 (0.8)2 (0.8)004 (1.6)253 (98.4)
  1. MCV Mean corpuscular volume, MCH mean corpuscular hemoglobin, BTT β-thalassemia traits, ETT, HbE traits HbE disease refers to the homozygous states of HbE, whereas non-carrier status is defined as “Normal”