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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Protein signature of human skin fibroblasts allows the study of the molecular etiology of rare neurological diseases

Fig. 1

Overview of subcellular compartments (a, b) and NMDs (c) covered by the created fibroblast library: a, b Presentation of the different subcellular fibroblast compartments including the corresponding number of proteins identified to be localized to these respective compartments. While some proteins are exclusively present in one compartment, a considerable number of such localized to different/multiple compartments is covered in the library. Proteins listed for the subcellular compartments illustrated in b might be also covered in a as being resident to membranes or the cytosol. c Illustrates the distribution of proteins identified for certain NMDs along the neuromuscular axis including motoneuron and peripheral nervous system diseases, defects in neuromuscular transmission and muscular disorders

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172