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Table 2 Clinical variables against time on PKU diet—M (SD)

From: The effect of improved dietary control on cognitive and psychiatric functioning in adults with phenylketonuria: the ReDAPT study

Clinical variable

Baseline

6 Months

12 Months

HAM-A

18.6 (8.03)

14.0 (9.27)

9.33 (4.89)

HAM-D

13.1 (5.82)

9.50 (9.06)

7.50 (6.66)

CPI

91.9 (8.21)

95.4 (6.78)

99.4 (5.40)

PSI

94.9 (8.65)

97.3 (7.89)

106 (8.09)

WMI

90.7 (8.69)

94.1 (9.51)

93.6 (6.48)

Delta-Phe

0 (0)

− 476 (290)

− 372 (250)

  1. HAM-A, Hamilton Anxiety Rating Scale; HAM-D, Hamilton Depression Rating Scale; CPI, Cognitive Proficiency Index; PSI, Processing Speed Index; WMI, Working Memory Index; Delta-Phe, Change in Phenylalanine