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Table 1 Treatment attributes and levels

From: Treatment preference among patients with spinal muscular atrophy (SMA): a discrete choice experiment

Category

Attribute

Levels

Code

Motor function

Level of change in motor function

Stable

1

Better

2

Breathing function

Level of change in breathing function

Stable

1

Better

2

Indication

Drug is approved for

Pediatric and adult patients with SMA

1

Pediatric patients with SMA only (e.g., < 2 years of age)

2

Route and frequency of administration

Route and frequency of treatments

Intravenous (IV) infusion—one-time treatment

1

Intrathecal (IT) spinal injection—3–6 times per year

2

Oral—daily medication

3

Potential harm

Treatments potentially raise severity of harm to patients

Mild risk which may involve minimal or non-invasive medical intervention

1

Moderate risk which may require medical intervention (possibly invasive), but not life threatening

2

Serious, or life-threatening risk which may require urgent medical intervention or prolonged hospitalization

3