Fig. 2

Association between executive function (ECAS domain) and motor function (HFMSE) in adult patients with SMA (N = 25). Dark blue = SMA type II, light blue = SMA type III ECAS = Edinburgh Cognitive and Behavioural ALS (amyotrophic lateral sclerosis) Screen, domain for “executive function” (score 0–48); HFMSE = Hammersmith Functional Motor Scale Expanded measures physical function on a scale from 0 to 66; the data point labelled “2”, represents two patients, the one labelled “4”, represents four patients; the data show a significant inverse correlation of executive and physical function (τ = − 0.36, p = 0.018)