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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: The International Collaborative Gaucher Group GRAF (Gaucher Risk Assessment for Fracture) score: a composite risk score for assessing adult fracture risk in imiglucerase-treated Gaucher disease type 1 patients

Fig. 1Fig. 1Fig. 1

Total GRAF Score by ATI Cohort. The total risk score (Gaucher Risk Assessment for Fracture [GRAF] score) and the individual risk factor estimates from the Cox proportional hazards regression for first fracture (any type) in adulthood after treatment initiation are plotted by each age at treatment initiation (ATI) cohort in panels A through C. Panel A includes the forest plots for the < 18 years ATI cohort. Panel B includes the forest plots for the ≥ 18 to < 50 years ATI cohort. Panel C includes the forest plots for the ≥ 50 years ATI cohort. Panels D through F are the corresponding forest plots of the GRAF score and individual risk factor estimates for the secondary spinal fractures analyses. CI = confidence interval; Dx = diagnosis; NA = not applicable; Tx = treatment

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172