Table 2 Association of BDNF and NfL in CSF and clinical scales
From: Fingolimod in children with Rett syndrome: the FINGORETT study
Clinical Score | estimate | Mult.effect | CI | p |
|---|---|---|---|---|
BDNF | ||||
RSSS | − 0.04 | 0.96 | [0.94; 0.98] | 0.03 |
HAS | − 0.09 | 0.91 | [0.89; 0.94] | < 0.01 |
VABS communication skills | 0.03 | 1.03 | [1.02; 1.04] | < 0.01 |
VABS daily living skills | 0.03 | 1.03 | [1.02; 1.04] | < 0.01 |
VABS social skills | 0.07 | 1.08 | [1.05; 1.11] | < 0.01 |
VABS motor skills | 0.04 | 1.04 | [1.03; 1.06] | 0.02 |
NfL | ||||
RSSS | 0.02 | 1.03 | [1.00; 1.05] | 0.28 |
HAS | 0.03 | 1.03 | [0.99; 1.08] | 0.45 |
VABS communication skills | 0.00 | 1.00 | [1.00; 1.01] | 0.8 |
VABS daily living skills | − 0.00 | 1.00 | [0.98; 1.01] | 0.75 |
VABS social skills | − 0.01 | 0.99 | [0.97; 1.01] | 0.53 |
VABS motor skills | − 0.01 | 0.99 | [0.97; 1.00] | 0.43 |