Skip to main content

Table 2 Association of BDNF and NfL in CSF and clinical scales

From: Fingolimod in children with Rett syndrome: the FINGORETT study

Clinical Score estimate Mult.effect CI p
BDNF     
 RSSS  − 0.04 0.96 [0.94; 0.98] 0.03
 HAS  − 0.09 0.91 [0.89; 0.94] < 0.01
 VABS communication skills 0.03 1.03 [1.02; 1.04] < 0.01
 VABS daily living skills 0.03 1.03 [1.02; 1.04] < 0.01
 VABS social skills 0.07 1.08 [1.05; 1.11] < 0.01
 VABS motor skills 0.04 1.04 [1.03; 1.06] 0.02
NfL
 RSSS 0.02 1.03 [1.00; 1.05] 0.28
 HAS 0.03 1.03 [0.99; 1.08] 0.45
 VABS communication skills 0.00 1.00 [1.00; 1.01] 0.8
 VABS daily living skills  − 0.00 1.00 [0.98; 1.01] 0.75
 VABS social skills  − 0.01 0.99 [0.97; 1.01] 0.53
 VABS motor skills  − 0.01 0.99 [0.97; 1.00] 0.43
  1. RSSS Rett Severity Scale, HAS Hand Apraxia Scale, VABS Vineland Adaptive Behaviour Scale