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Table 5 Onset of cardiovascular manifestations with respect to HSCT

From: Long term disease burden post-transplantation: three decades of observations in 25 Hurler patients successfully treated with hematopoietic stem cell transplantation (HSCT)

 

Before HCST

After HCST

Total

n

(%)

Age (years)

n

(%)

Age (years)

Median

Range

Median

Range

N

M- dysplasia

18

72

1 year 4 months

10 months–3 year 5 months

7

28

8 years 8 months

3 years 6 months–19 years

25

A- dysplasia

10

40

1 year 4 months

11 months–2 years 10 months

11

44

7 years 10 months

2–29 years

21

M- regurgitation

14

56

1 year 4 months

10 months–3 years 5 months

11

44

4 years 5 months

2–19 years

25

A- regurgitation

2

8

1 year 6 months

1 year 4 months –1 year 8 months

14

56

11 years 7 months

3 years 6 months–21 years 11 months

16

Stenosis

0

–

–

–

6

24

15 years 6 months

7 years 5 months–21 years 11 months

6

Surgery

0

–

–

–

1

4

34 years 11 months

 

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