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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Neonatal hyperinsulinism in transient and classical forms of tyrosinemia

Fig. 1

Adapted from Cardinale et al. [12]

Common origin for the development of pancreatic β-cells form from bile duct epithelium. It could be postulated that abnormal development of liver cells or abnormalities within the biliary tree could affect the appropriate development and/or function of future pancreatic cells. The diagram is an adapted proposal illustrating a possible path to the development of pancreatic β-cells.

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