Orphanet Journal of Rare Diseases

Table 1 Reference ranges

From: Eye movement biomarkers allow for the definition of phenotypes in Gaucher Disease

	Mean value	Reference range
Response time^a
Left/ms	205	144–267
Right/ms	213	149–277
Up/ms	197	147–246
Down/ms	213	145–281
Saccade duration^b
Left/%	99	76–122
Right/%	98	74–123
Up/%	113	58–167
Down/%	118	75–161
Saccade peak velocity^c
Left (10°)/(°/s)	325	244–405
Left (20°)/(°/s)	448	338–556
Right (10°)/(°/s)	312	240–385
Right (20°)/(°/s)	447	342–552
Up (10°)/(°/s)	316	236–397
Up (20°)/(°/s)	443	293–594
Down (10°)/(°/s)	310	238–382
Down (20°)/(°/s)	398	299–497
Saccade gain^d
Left/%	94	85–103
Right/%	90	80–101
Up/%	88	70–105
Down/%	97	80–116

Data are provided as the population mean and the 95% prediction interval as computed for the healthy control cohort (n = 29)
^aTime duration from target onset to saccade onset
^bTime duration from saccade onset to saccade end obtained from readouts of the linear amplitude—saccade duration fit at 20° for each individual
^cPeak saccade velocity obtained from readouts at 10° and 20° from the individual’s fit along the main sequence
^dRatio of saccade amplitude and target amplitude obtained from readouts of the target distance—gain fit at 20° for each individual

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ISSN: 1750-1172

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