Fig. 1

Aminotransferase values in all CDG patients according to type (a ALT values in PMM2-CDG patients. b AST values in PMM2-CDG patients. c ALT values in non-PMM2-CDG CDG-I patients. d AST values in non-PMM2-CDG CDG-I patients. e ALT values in CDG-II patients. f AST values in CDG-II patients). There is a notable inflexion point around 5 years of age in the figures A and B, after which most values tend to be normal or near-normal. A less defined inflexion point can be noted in the figures C and D at approximately 8 years of age, although there are still many patients with elevated values after this age