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Table 3 Threshold effect analysis of fibrinogen on survival using two-piecewise Cox proportional hazards regression models

From: The prognostic role of plasma fibrinogen in adult secondary hemophagocytic lymphohistiocytosis

Inflection point

Group

HR (95% CI)

P value

P for log likelihood ratio test

1.76

≤ 1.76

0.68 (0.55–0.83)

< 0.001

< 0.001

> 1.76

1.08 (0.96–1.21)

0.187

 
  1. Analyses were adjusted for age, PLT (platelet), EBV, log10-transform ferritin, MHLH and treatment strategies
  2. HR hazard ratio, CI confidence interval