Fig. 6From: Diagnostic journey and impact of enzyme replacement therapy for mucopolysaccharidosis IVA: a sibling control studyPhysical examination of the siblings. Patient 1 at 14 years of age, Patient 2 at 9 years of age, and Patient 3 at 3 years of age. Lordotic posture can be noted in all three patients. Prior to starting ERT, all three siblings showed skeletal abnormalities and walking impairment, which were more advanced in the oldest sibling (Patient 1)Back to article page