Fig. 2From: Diagnostic journey and impact of enzyme replacement therapy for mucopolysaccharidosis IVA: a sibling control studyRepresentative serial radiographs of the proximal right femur of Patient 1 over time show progressive flattening of the epiphysis, concomitant widening of the proximal metaphyses, and increased irregularity of the acetabula resulting in compensatory pseudarthrosis-like formationBack to article page