Table 1Â Urine creatine panel metabolites and their age and sex related distribution
From: Urine creatine metabolite panel as a screening test in neurodevelopmental disorders
Urine creatine panel metabolites | Age dependent reference range | Numbers | Female | Male | Statistical analysis (non-parametric Kruskal–Wallis rank sum test) |
|---|---|---|---|---|---|
Number | Number | ||||
Mean ± SD | Mean ± SD | ||||
Range | Range | ||||
Urine guanidinoacetate | 0–60 months (Reference range 5–150 mmol/mol creatinine) | Number | 58 | 109 | p = 0.001856* |
|  |  | Average ± SD | 104.0 ± 51.9 | 81.81 ± 44.3 |  |
| Â | Â | Median | 100 | 71 | Â |
|  |  | Range | 15.0–250.0 | 9.00–281.00 |  |
| Â | Â | 2.5th percentile | 25 | 26 | Â |
| Â | Â | 25th percentile | 61 | 54.25 | Â |
| Â | Â | 75th percentile | 138.5 | 93.75 | Â |
| Â | Â | 97.5th percentile | 204.9 | 195.5 | Â |
|  | 60–192 months (reference range 15–130 mmol/mol creatinine) | Number | 48 | 67 | p = 0.569 |
|  |  | Average ± SD | 64.25 ± 39.6 | 69.21 ± 87.8 |  |
| Â | Â | Median | 54 | 54 | Â |
|  |  | Range | 8–171 | 1–573 |  |
| Â | Â | 2.5th percentile | 10.275 | 10.625 | Â |
| Â | Â | 25th percentile | 37 | 34.25 | Â |
| Â | Â | 75th percentile | 85.7 | 78.5 | Â |
| Â | Â | 97.5th percentile | 151.625 | 237.025 | Â |
|  | 192–228 months (reference range 11–60 mmol/mol creatinine) | Number | 6 | 9 | p = 0.07825 |
|  |  | Average ± SD | 60.86 ± 29.1 | 34.90 ± 15.8 |  |
| Â | Â | Median | 44 | 34 | Â |
|  |  | Range | 29–97 | 13–65 |  |
| Â | Â | 2.5th percentile | 30.35 | 13.9 | Â |
| Â | Â | 25th percentile | 39.5 | 24.5 | Â |
| Â | Â | 75th percentile | 88.5 | 42.75 | Â |
| Â | Â | 97.5th percentile | 96.4 | 61.4 | Â |
Urine creatine | 0–60 months (reference range 14–830 mmol/mol creatinine) | Number | 58 | 109 | p = 0.03946* |
|  |  | Average ± SD | 777.3 ± 490.0 | 645.6 ± 537.0 |  |
| Â | Â | Median | 720 | 533.5 | Â |
|  |  | Range | 14.0–2333.0 | 4.0–3915.0 |  |
| Â | Â | 2.5th percentile | 31.85 | 13.925 | Â |
| Â | Â | 25th percentile | 383 | 327.5 | Â |
| Â | Â | 75th percentile | 1059 | 885.2 | Â |
| Â | Â | 97.5th percentile | 1710.75 | 1844.43 | Â |
|  | 60–192 months (reference range 16–649 mmol/mol creatinine) | Number | 48 | 67 | p = 0.8339 |
|  |  | Average ± SD | 424.83 ± 1217.0 | 290.8 ± 471.0 |  |
| Â | Â | Median | 153 | 161 | Â |
|  |  | Range | 3.00–8756.00 | 3.0–3518.0 |  |
| Â | Â | 2.5th percentile | 5.825 | 4 | Â |
| Â | Â | 25th percentile | 25.25 | 28 | Â |
| Â | Â | 75th percentile | 398.25 | 389 | Â |
| Â | Â | 97.5th percentile | 1080.78 | 907.075 | Â |
|  | 192–228 months | Number | 6 | 9 | p = 0.6594 |
|  | (reference range 19–173 mmol/mol creatinine) | Average ± SD | 47.0 ± 64.6 | 68.6 ± 164.0 |  |
| Â | Â | Median | 17 | 11 | Â |
|  |  | Range | 5.0–186.0 | 5.0–531.0 |  |
| Â | Â | 2.5th percentile | 5.4 | 5.225 | Â |
| Â | Â | 25th percentile | 9 | 8 | Â |
| Â | Â | 75th percentile | 51.5 | 16.5 | Â |
| Â | Â | 97.5th percentile | 167.1 | 428.625 | Â |