From: Estimated prevalence of mucopolysaccharidoses from population-based exomes and genomes
Gene | Disease-causing variants | CI in 100,000 (max) | CI in 100,000 (min) |
---|---|---|---|
IDUA | 259 | 7.103–7.096 | 2.479–2.476 |
IDS | 29 | 0.0108–0.0107 | 0.00014–0.00013 |
SGSH | 236 | 2.365–2.363 | 0.4116–0.4112 |
NAGLU | 225 | 1.532–1.530 | 0.366–0.365 |
HGSNAT | 159 | 1.566–1.565 | 0.107–0.106 |
GNS | 127 | 0.459–0.458 | 0.0549–0.0548 |
GALNS | 224 | 2.363–2.361 | 0.25–0.25 |
GLB1* | 225 | 1.677–1.676 | 0.456–0.455 |
ARSB | 188 | 1.119–1.117 | 0.1761–0.1758 |
GUSB | 224 | 1.144–1.141 | 0.2081–0.2078 |
HYAL1 | 141 | 0.4393–0.4388 | 0.1081–0.1079 |