Urinary EVs/mg creatinine | Markers | Primary Hyperoxaluria Type 1 (PH1) | Statistical Results | |||
---|---|---|---|---|---|---|
PH1 without NC or KS (n = 10) | PH1 with NC (n = 6) | PH1 with KS (n = 9) | p value | Q value | ||
EV generation from plasma membrane | Anoctamin 4 | 12.6 (11.9, 13.8) | 13.0 (11.7, 14.5) | 11.3 (11.0, 11.6) | 0.05 | 0.13* |
Endocytosis mediated EV generation | Huntington interacting protein 1 | 11.9 (10.6, 13.2) | 11.5 (10.7, 14.1) | 10.2 (9.9, 10.8) | 0.14 | 0.17* |
Renal calcium/phosphate homeostasis regulators | Klotho | 13.0 (12.5, 13.9) | 12.3 (12.1, 14.2) | 11.6 (10.3, 12.0) | 0.04 | 0.13* |
Fibroblast growth factor 23 | 11.4 (11.1, 11.7) | 10.9 (10.5, 11.2) | 10.6 (10.2, 10.9) | 0.26 | 0.28 | |
Phosphate transporter 1 (PiT1) | 11.8 (11.5, 12.7) | 11.6 (10.9, 12.1) | 11.0 (10.3, 11.2) | 0.15 | 0.19* | |
Phosphate transporter 2 (PiT1) | 12.3 (11.5, 13.5) | 12.4 (11.5, 14.2) | 11.2 (10.8, 12.4) | 0.11 | 0.17* |