Skip to main content

Table 2 Comparison of biochemical data between different gender groups and between different phenotypes

From: Clinical and molecular characteristics of 69 Chinese patients with ornithine transcarbamylase deficiency

 

CIT

(μmol/L)

GLN

(μmol/L)

Orotic acid

(mmol/molCr)

Uracil

(mmol/molCr)

AMON

(μmol/L)

Reference values

7–35

6–30

0–1.5

0–7

9–30

Male (n = 34)

4.1 (29)

15.1 (23)

193.8 (24)

53.3 (25)

335 (33)

Range

1.1–25.4

3.3–80.6

1.8–1638.3

5.7–339.1

45–2500

Female (n = 34)

9.2 (34)

20.8 (31)

198.9 (32)

79.0 (29)

273 (34)

Range

1.8–19.2

4.9–61.7

2.7–1435.3

6.8–559.2

59–2000

Z

− 3.061

− 1.268

− 0.248

− 1.795

− 1.117

P

0.002

0.205

0.804

0.073

0.264

EO (n = 15)

3.3 (12)

29.7 (9)

249.4 (10)

52.5 (10)

679 (14)

Range

1.7–14.8

3.3–80.6

22.3–1638.3

8.6–256.5

50–2000

LO (n = 53)

8.4 (51)

17.7 (45)

181.0 (46)

75.4 (44)

265 (53)

Range

1.1–25.4

4.9–61.7

1.8–1435.3

5.7–559.2

45–2500

Z

− 3.326

− 1.938

− 1.455

− 1.336

− 3.726

P

0.001

0.053

0.146

0.182

0.000

  1. Quantitative data were expressed as the median (number of patients tested) and the range (minimum–maximum)
  2. EO, early onset patients; LO, late onset patients