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Table 2 Urodynamic data

From: Beyond gait and balance: urinary and bowel dysfunction in X-linked adrenoleukodystrophy

ID Phenotype Sex Age (yrs) First sensation (mL) Maximum cystometric capacity (mL) Bladder pressure study Pdet@Qmax (cm H2O) Qmax (mL/s) EMG finding Vesical wall Impression
1 AMN F 63.6 "Very early in filling phase" Normal 14 10 smooth Neurogenic hypocontractile detrusor
2 AMN F 80.2 112 263 Phasic detrusor contractions 56 11 Synergy Smooth NDO
3 AMN M 57.4 155 155 No phasic detrusor contractions 13 5 Synergy Markedly trabeculated NDO, impaired contractility
4Aa CALD post-HSCT M 21.9 195 411 No phasic detrusor contractions 42 19 Synergy Smooth Normal
4Ba CALD post-HSCT M 23.2 62 139 Phasic detrusor contractions 26 11 Sphincter dyssynergia NTDO with DSD
5 AMN, self-halted CALD M 28.2 32 216 Phasic detrusor contractions 66 9 Synergy Smooth NDO, BOO, multi-phasic micturition
6 AMN, self-halted CALD M 36.3 30–45 43 Terminal detrusor overactivity 62 3 Sphincter dyssynergia Moderately trabeculated NTDO with DSD
7 AMN, self-halted CALD M 20.9 262 348 No phasic detrusor contractions 47 15 Synergy Smooth NTDO, neurogenic delay in sensory arm
8 AMN F 47.2 130 431 Phasic detrusor contractions 8 3 Synergy Smooth NDO
9 AMN F 47.2 132 545 Phasic detrusor contractions 20 10 Synergy Smooth NDO, impaired contractility
10 AMN M 46.9 78 293 Phasic detrusor contractions 56 11 Synergy Smooth severe NDO
11 AMN, self-halted CALD M 34.8 286 359 Phasic detrusor contractions 51 11 Synergy Smooth NDO
  1. Summary of urodynamic patient data collected at Massachusetts General Hospital, describing a diverse array of neurogenic bladder presentations
  2. aPatient 4 had urodynamic studies performed at two timepoints
  3. BOO, bladder outlet obstruction; DSD, detrusor sphincter dyssynergia; HSCT, hematopoietic stem cell transplant; NDO, neurogenic detrusor overactivity; NTDO, neurogenic terminal detrusor overactivity; Pdet, detrusor pressure; Qmax, peak urinary flow rate