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Table 1 Onset age for each urinary and bowel symptom and myelopathy symptoms among males and females

From: Beyond gait and balance: urinary and bowel dysfunction in X-linked adrenoleukodystrophy

 

Males

Females

Equality of distributions

n

Median (95% CI)

n

Median (95% CI)

Chi-squared (p value)

Urinary frequency

51

35 (30; 38)

46

57 (36; 63)

7.623 (0.006)**

Urinary urgency

40

34 (26; 35)

45

50 (40; 58)

10.672 (0.001)**

Urinary incontinence

53

38 (35; 45)

52

50 (42; 55)

4.953 (0.026)*

Urinary hesitancy

48

38 (32; 45)

45

68 (55; 69)

12.092 (< 0.001)**

Urinary retention

47

42 (35; –a)

39

58 (50; 69)

5.018 (0.025)*

Fecal urgency

36

37 (26; 45)

37

54 (43; 62)

4.913 (0.027)*

Fecal incontinence

47

44 (36; 48)

48

54 (46; 62)

3.759 (0.053)

Constipation

50

41 (30; 45)

48

53 (40; 59)

3.468 (0.063)

Diarrhea

48

58 (47; 58)

48

53 (45; 63)

0.037 (0.848)

At least one urinary symptom

56

28 (25; 30)

52

38 (35; 47)

17.937 (< 0.001)**

At least one bowel symptom

52

30 (22; 40)

52

41 (33; 53)

2.391 (0.122)

At least one urinary or bowel symptom

56

25 (10; 28)

52

35 (30; 41)

9.096 (0.003)**

Myelopathy

56

30 (28; 32)

53

43 (38; 48)

26.158 (< 0.001)**

  1. Median point estimate of onset age in years for each urinary and bowel symptom and myelopathy symptoms, using generalized log-rank test to calculate equality distributions between males and females
  2. aModel unable to compute value due to limited sample size within extremes of age distribution
  3. *p < .05
  4. **p < .01