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Table 1 Onset age for each urinary and bowel symptom and myelopathy symptoms among males and females

From: Beyond gait and balance: urinary and bowel dysfunction in X-linked adrenoleukodystrophy

  Males Females Equality of distributions
n Median (95% CI) n Median (95% CI) Chi-squared (p value)
Urinary frequency 51 35 (30; 38) 46 57 (36; 63) 7.623 (0.006)**
Urinary urgency 40 34 (26; 35) 45 50 (40; 58) 10.672 (0.001)**
Urinary incontinence 53 38 (35; 45) 52 50 (42; 55) 4.953 (0.026)*
Urinary hesitancy 48 38 (32; 45) 45 68 (55; 69) 12.092 (< 0.001)**
Urinary retention 47 42 (35; –a) 39 58 (50; 69) 5.018 (0.025)*
Fecal urgency 36 37 (26; 45) 37 54 (43; 62) 4.913 (0.027)*
Fecal incontinence 47 44 (36; 48) 48 54 (46; 62) 3.759 (0.053)
Constipation 50 41 (30; 45) 48 53 (40; 59) 3.468 (0.063)
Diarrhea 48 58 (47; 58) 48 53 (45; 63) 0.037 (0.848)
At least one urinary symptom 56 28 (25; 30) 52 38 (35; 47) 17.937 (< 0.001)**
At least one bowel symptom 52 30 (22; 40) 52 41 (33; 53) 2.391 (0.122)
At least one urinary or bowel symptom 56 25 (10; 28) 52 35 (30; 41) 9.096 (0.003)**
Myelopathy 56 30 (28; 32) 53 43 (38; 48) 26.158 (< 0.001)**
  1. Median point estimate of onset age in years for each urinary and bowel symptom and myelopathy symptoms, using generalized log-rank test to calculate equality distributions between males and females
  2. aModel unable to compute value due to limited sample size within extremes of age distribution
  3. *p < .05
  4. **p < .01