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Table 1 Demographic and clinical features of KHE patients with or without lymphedema

From: Chronic lymphedema in patients with kaposiform hemangioendothelioma: incidence, clinical features, risk factors and management

Variables

Without lymphedema

With lymphedema

Total

P

n = 105

n = 13

n = 118

Patients

    

Sex

   

0.566§

 Male

54 (51.4)

8 (61.5)

62 (52.5)

 

 Female

51 (48.6)

5 (38.4)

56 (47.5)

 

Age at discovery of tumor (m)

   

0.559#

 Mean (range)

21.3 (0.0–576.0)

5.2 (0.0–12.0)

19.5 (0.0–576.0)

 

 Median (IQR)

1.0 (0.0–6.8)

3.5 (0.3–7.5)

1.5 (0.0–6.6)

 

Age at diagnosis of KHE (m)

   

0.208#

 Mean (range)

28.4 (0.0–600.0)

13.5 (0.0–27.0)

26.8 (0.0–600.0)

 

 Median (IQR)

2.3 (1.0–6.0)

2.1 (1.3–6.1)

2.2 (1.0–6.0)

 

KMP

   

0.366§

 With KMP

64 (61.0)

10 (76.9)

74 (62.7)

 

 Without KMP

41 (39.0)

3 (23.1)

44 (37.3)

 

KHE

    

Location

   

0.006§

 Extremity involvement

55 (52.4)

13 (100.0)

68 (57.6)

 

 Non-extremity involvement

50 (47.6)

0 (0)

50 (42.4)

 

Morphology

   

0.009

 Superficial

30 (28.6)

0 (0)

30 (25.4)

 

 Mixed

59 (56.2)

13 (100.0)

72 (61.0)

 

 Deep

16 (15.2)

0 (0)

16 (13.6)

 

Tumor size (cm)

   

0.001§

  < 10 cm

77 (73.3)

3 (23.1)

80 (67.8)

 

 ≥ 10 cm

28 (26.7)

10 (76.9)

38 (32.2)

 
  1. KHE Kaposiform hemangioendothelioma, KMP, Kasabach–Merritt phenomenon, m month, IQR interquartile range
  2. Values are presented as the number of cases (percentage)
  3. Patients with lymphedema compared to patients without lymphedema
  4. §P value was calculated with Fisher’s exact test
  5. P value was calculated using the Pearson chi-square test
  6. #P value was calculated using the Mann–Whitney U test