Fig. 1From: Pyruvate dehydrogenase complex deficiency: updating the clinical, metabolic and mutational landscapes in a cohort of Portuguese patientsMagnetic resonance images of brain lesions of an 8 month old patient carrying a PDHA1 mutation. Hyperintense bilateral and symmetrical lesions in the thalami, globus pallidus and putamina, on T2 weighted images, hypointense on T1 and with diffusion restriction suggestive of acute lesions; there is no diffusion restriction suggestive of chronic lesions. a axial T2, b axial T1 IR, c axial DWI, d axial ADCBack to article page