Fig. 4
From: Novel GANAB variants associated with polycystic liver disease
Localization of wild-type and mutant GIIα in HeLa cells. Immunofluorescence staining of HeLa cells transfected with GANAB Wild Type (WT; a–c) and variants c.11_16delTAGCGG (11; d–f), c.687delT (687; g–i) and c.2002+1G>C (int; j–l). GIIα (green) staining shows co-localization to GIIβ (red) with WT and variant 11 where variant 687 shows localization throughout the cell and splice variant int localizes to the nucleus (blue)