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Table 2 Cox regression results of HHT manifestations and gene mutations

From: Predictors of mortality in patients with hereditary hemorrhagic telangiectasia

Characteristic HR 95% CI p value
Brain VM 0.76 (0.35, 1.66) 0.494
Pulmonary AVM 1.12 (0.64, 1.96) 0.681
Symptomatic Liver VM 2.10 (1.15, 3.84) 0.015
GI bleeding 2.63 (1.46, 4.74) 0.001
Anemia 2.93 (1.37, 6.26) 0.006
ACVRL1 (vs. ENG) 1.54 (0.70, 3.38) 0.286
SMAD4 (vs. ACVRL1/ENG) 18.36 (5.60, 60.20)  < 0.001
  1. Characteristics were tested individually, while adjusting for age, sex, and smoking status