Fig. 2

Functional impairment of patients with ATTR-FAP. a World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). The scores assigned to each of the 12 items (“none” 0, “mild” 1, “moderate” 2, “severe” 3 and “extreme” 4) are summed for each individual patient. This summed score is divided by 48 and multiplied by 100 in order to determine a functioning level ranging from 0% (full function) to 100% (no function) for each individual respondent. Base population: All respondents (n = 38). b World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). Functional impairment based on the individual items: day-to-day work, maintaining a friendship, dealing with foreign people, getting dressed, washing your body, concentrating on doing something for more than 10 min, joining in community activities, learning a new task, taking care of household responsibilities, walking a long distance such as a kilometer and standing for long periods such as 30 min. The scores assigned to each of the above-mentioned items (“none” 0, “mild” 1, “moderate” 2, “severe” 3 and “extreme” 4) are summed for each item across all patients. This summed score is divided by 152 and multiplied by 100 in order to give a disability score ranging from 0% (full function) to 100% (no function). Base population: All respondents (n = 38). c Patient reported mental health. Base population: All respondents (n = 38). Question: In the past 30 days, how much have you been emotionally affected by your health problems?