Fig. 2From: Phenotypic and genetic spectrum of isolated macrodactyly: somatic mosaicism of PIK3CA and AKT1 oncogenic variantsDistribution of PIK3CA variants identified in this study by functional domains. ABD: PI3K-ABD domain. RBD: PI3K-RBD domain. C2: C2 PI3K-type domain. Helical: PIK helical domain. Kinase: PI3K/PI4K kinase domain. A dot represents a PIK3CA variant identified in one patientBack to article page