Table 3 Negative biopsy cases for nine patients among ATTRv amyloidosis patients diagnosed within three years from the initial biopsy
Sex | Age | Mut | Phenotype | Onset | Fibrils | 2nd fat Bx | Other Bx | Dx per | |
|---|---|---|---|---|---|---|---|---|---|
1 | F | 74 | V30M | PN, eye | Late | NA | − | CT+ | CT Bx |
2 | M | 67 | V30M | PN | Late | NA | + | GI+ | Fat/GI Bx |
3 | M | 72 | V30M | PN, CM, GI | Late | NA | + | ND | Fat Bx/DPD |
4 | F | 64 | V30M | PN, GI, eye | Late | NA | ND | Skin+ | Skin Bx |
5 | M | 66 | V122I | CM | Late | NA | ND | Heart+ | Heart Bx |
6 | M | 62 | V30M | PN, CM | Late | Type B | + | ND | Fat Bx/DPD |
7 | M | 58 | V30M | PN, CM | Late | NA | − | ND | DPD |
8 | M | 52 | V30M | PN, CM | Late | NA | + | ND | Fat Bx/DPD |
9 | M | 46 | V30M | PN, GI | Early | NA | − | GI− | Clin. picture |