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Table 1 Baseline patient characteristics

From: Abdominal fat pad biopsies exhibit good diagnostic accuracy in patients with suspected transthyretin amyloidosis

  Male (n = 167) Female (n = 107) All (n = 274)
Age (full range) 61 (24–88) years 60 (21–86) years 60 (21–88) years
Genotype
 TTR mutation 105 (63%) 71 (66%) 176 (64%)
 V30M 101 (96%) 70 (99%) 171 (97%)
 Other 4 (4%) 1 (1%) 5 (3%)
 No TTR mutation 26 (16%) 17 (16%) 43 (16%)
 Not tested 36 (21%) 19 (18%) 55 (20%)
Symptom/findinga
 Polyneuropathy 146 (87%) 100 (93%) 246 (90%)
 Cardiomyopathy 62 (35%) 17 (16%) 79 (29%)
 GI symptoms 43 (26%) 41 (38%) 84 (31%)
 Eye complications 21 (13%) 26 (24%) 47 (17%)
 Other symptoms 1 (0.5%) 2 (2%) 3 (1%)
Echocardiogram
 IVSd ≥ 12 mm 68 (72%) 25 (45%) 93 (62%)
 IVSd < 12 mm 26 (28%) 31 (55%) 57 (38%)
99mTc-DPD scint
 Positive 18 (78%) 6 (46%) 24 (67%)
 Negative 5 (22%) 7 (54%) 12 (33%)
Amyloid in first Bx 70 (42%) 39 (36%) 109 (40%)
  1. aEach individual can present with one or more symptom/finding; Bx: biopsy; GI: gastrointestinal; IVSd: interventricular septum diameter; scint: scintigraphy; TTR: transthyretin gene. Percentages are shown as column percentage within each heading/subheading