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Table 2 Levels of FXII and the hypoglycosylated form of FXII as well as other markers of hypoglycosylation in PMM2-CDG patients according to the presence or absence of vascular events

From: Factor XII in PMM2-CDG patients: role of N-glycosylation in the secretion and function of the first element of the contact pathway

 

Vascular events (N = 20)

No vascular complications (N = 26)

p

FXII:C (%)

113 ± 48%

120 ± 41%

0.728

1 N/2 N FXII ratio

1.26 ± 0.04

0.54 ± 0.28

0.003

Asialo-transferrin (%)

33.5 ± 12.9

21.9 ± 15.1

0.077

Disialo-trasnferrin (%)

12.8 ± 8.4

4.5 ± 5.3

0.013

Antithrombin (%)

40.6 ± 23.9

72.0 ± 31.1

0.001

FXI (%)

35.6 ± 26.0

74.9 ± 36.30

0.001

  1. Statistically significant p-values (≤ 0.05) are shown in italics
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172