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Fig. 5 | Orphanet Journal of Rare Diseases

Fig. 5

From: Factor XII in PMM2-CDG patients: role of N-glycosylation in the secretion and function of the first element of the contact pathway

Fig. 5

Electrophoretic analysis of the recombinant FXII. Its was secreted into the culture medium (supernatant) and in the cell lysate (intracellular) of Drosophila Schneider 2 cells transfected with the plasmid of wild-type human FXII (WT) or with the following mutations: p.Asn414Lys (414); p.Asn230Lys (230); p.Thr309Lys (309) or the double mutation p.Asn414Lys&p.Asn230Lys (Double)

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172