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Table 6 Comorbidities reported

From: Data from the European registry for patients with McArdle disease and other muscle glycogenoses (EUROMAC)

Comorbidities

N

Frequency in this Cohort (n = 241) (%)

Median age (range) Years

Hypertension

41

17

57 (39–82)

Endocrine disease (Total)

38

15.7

56 (17–77)

 Diabetes

15

 Hypothyroidism

14

 Thyrotoxicosis

2

 Thyroid tumour

2

 Hyperthyroidism

2

 Other endocrine problems

3

Musculoskeletal/rheumatic disease

31

12.9

52 (15–82)

Coronary artery disease

20

8.3

62 (42–80)

Other cardiovascular disease

10

4.1

54.5 (35–80)

Hyperuricemia/gout

28

11.6

60.5 (24–80)

Gastroenterological disease (Total)

27

11.2

52 (12–77)

 Gall bladder problems

6

 Hiatus hernia and/or acid reflux

4

 Crohn’s disease

3

 Irritable bowel syndrome

3

 Coeliac disease

3

 Diverticulitis or polyposis

2

 Constipation

1

 Gastritis

1

 Liver diseasea

4a

 Pancreatitisa

2a

Neurological disease

24

10

51.5 (13–81)

Respiratory disease

23

9.5

51 (12–75)

Acute renal failure

19

7.9

53 (33–76)

Chronic renal failure

3

1.2

44 (17–49)

Dyslipidaemia

21

8.7

57 (24–82)

Mental disorder (Total)

16

6.6

49 (13–75)

 Depression

9

 Anxiety

4

 Bipolar disorder

1

 Schizophrenia

1

 Post-traumatic stress disorder

1

Cancer

11

4.6

55 (33–82)

Anaemia/hyperbilirubinemia

9

3.7

39 (26–82)

Ophthalmological disease

5

2.1

67 (60–73)

Others

54

22.4

53 (19–80)

  1. aTwo patients had two gastroenterological diseases: Thus, the sum in the table is higher than the total number of patients affected by a gastroenterological disease