Table 3 Comparison of clinical features of low- and elevated-GMAb HP patients
Characteristics | Low-GMAb (n = 40) | Elevated-GMAb (n = 5) | p-value |
|---|---|---|---|
Age, years | 59.5 [50.5–68.5] | 71 [64.5–73.5] | 0.039 |
Male, n | 23 [57.5] | 2 [40] | 0.652 |
Chronic HP, n | 35 [87.5] | 5 [100] | 1.000 |
Trichosporon asahii, n | 5 [14.7] | 1 [20] | 1.000 |
BAL Ly, % | 17.4 [8.1–79.9] | 69.9 [47.8–81.1] | 0.019 |
BAL CD4/CD8 | 1.7 [0.62–3.95] | 2.1 [1.1–8.6] | 0.437 |
LDH, U/L | 208 [196–258] | 236 [211–327] | 0.213 |
KL-6, U/mL | 1416 [797–2457] | 4638 [3430–9674] | 0.001 |
SP-D, ng/mL | 180 [102–339] | 491 [330–689] | 0.004 |
SP-A, ng/mL | 59.5 [40.1–96.3] | 69.3 [51.0–150] | 0.426 |
CEA, ng/mL | 3.7 [2.4–6.2] | 6.1 [5.6–16.1] | 0.023 |
CYFRA, ng/mL | 2.8 [2.3–4.4] | 3.7 [2.9–5.3] | 0.001 |
%FVC, % | 83.1 [64.2–90.1] | 95.5 [82.4–116.9] | 0.108 |
%DLco, % | 64.3 [55.1–79.1] | 74.6 [56.6–79.5] | 0.627 |
Use of steroids, n | 15 [37.5] | 4 [80] | 0.146 |