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Table 3 Visual analogue scale (0–10) responses over the past week of patients with type I Gaucher disease

From: Patient reported outcome measures in a large cohort of patients with type 1 Gaucher disease

  All Untreated group Received GD-specific therapy p value**
1. Dependent on others because of your Gaucher disease? 1.31 (1.2–1.4) 1.09 (0.9–1.28) 1.45 (1.23–1.68) 0.001
2. Visibly big or swollen abdomen because of your Gaucher disease? 2.05 (1.8–2.3) 1.70 (1.29–2.12) 2.18 (1.85–2.52) 0.06
3. Fatigued because of your Gaucher disease? 2.88 (2.5–3.2) 1.69 (1.37–2.00) 3.59 (3.09–4.08) < 0.001
4. Physically weak because of your Gaucher disease? 2.73 (2.4–3.1) 1.70 (1.38–2.03) 3.39 (2.95–3.83) < 0.001
5. Severity of bone pain because of your Gaucher disease? 2.40 (2.1–2.7) 1.57 (1.26–1.89) 2.88 (2.41–3.36) < 0.001
6. Depressed because of your Gaucher disease? 1.62 (1.4–1.8) 1.35 (1.14–1.56) 1.80 (1.48–2.12) 0.18
7. Worried because of your Gaucher disease? 2.01 (1.7–2.3) 1.39 (1.17–1.60) 2.39 (1.99–2.78) 0.001
8. How have you felt about your future with Gaucher disease? 2.47 (2.2–2.8) 1.57 (1.28–1.87) 2.98 (2.55–3.41) < 0.001
  1. *Mean (95% confidence interval for the mean), ** Non-parametric independent samples Mann–Whitney test