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Table 2 Recommended Therapeutic Phenylalanine Treatment Ranges

From: Similarities and differences in key diagnosis, treatment, and management approaches for PAH deficiency in the United States and Europe

 

ACMG (2014)

European Guidelines (2017)

Recommended treatment ranges

 Infants (1 year or less)

120–360 μmol/L

< 360 μmol/L

 Children < 12

120–360 μmol/L

< 360 μmol/L

 Adolescents

120–360 μmol/L

> 600 μmol/L

 Adults > 18

120–360 μmol/L

< 600 μmol/L

 Women

  Prior to conception

120–360 μmol/L

< 360 μmol/L

  During Pregnancy

120–360 μmol/L

120–360 μmol/L