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Table 3 Comparison of clinical data between the groups of Kawasaki disease (KD) with and without Grisel syndrome (GS)

From: Grisel’s syndrome in Kawasaki disease

  KD with GS
(n = 10)
KD without GS
(n = 1254)
p value
Male, n (%) 2(20.0) 731(58.3) 0.021
Age, years 5.9(4.3–6.7) 2.2(1.2–3.6) <0.001
Clinical manifestations
 Rash 5(50.0) 939(74.9) 0.134
 Edema & erythema of the extremities 3(30.0) 715(57.0) 0.111
 Bilateral bulbar conjunctive injection 8(80.0) 1138(90.7) 0.226
 Erythema of oral and pharyngeal mucosa 8(80.0) 1142 (91.1) 0.256
 Cervical lymphadenopathy 10(100.0) 647(51.6) 0.002
 Fever duration before IVIG administration, days 6.0(4.8–7.3) 6.0(5.0–7.0) 0.916
 Incomplete KD 6(60.0) 460(36.7) 0.186
 IVIG resistance 0(0.00) 188(15.0) 0.374
 Coronary artery lesions 0(0.00) 125(10.6) 0.292
Laboratory examinations
 White blood cell, ×109/L 14.6(12.5–18.8) 14.0(11.0–17.4) 0.744
 Neutrophil count, % 79.9(77.2–91.7) 68.3(58.0–78.6) 0.001
 Hemoglobin, g/L 108.0(99.3–117.5) 109.0(102.0–116.0) 0.737
 Platelet count, ×109/L 313(268–350) 325(267–395) 0.344
 C-reactive protein, mg/L 111.0(69.5–155.5) 76.0(45.0–114.0) 0.155
 Erythrocyte sedimentation rate, mm/h 102.0(59.0–124.0) 66.0(46.0–87.0) 0.018
 Aspartate aminotransferase, U/L 34.5(27.0–56.5) 34.0(26.0–52.0) 0.573
 Alanine aminotransferase, U/L 25.5(13.0–39.0) 37.0(21.0–79.0) 0.332
 Albumin, g/L 36.0(31.7–42.3) 37.5(34.1–40.9) 0.667
 Total bilirubin, umol/L 9.2(7.1–15.5) 6.3(4.0–10.0) 0.858
 Creatinine, umol/L 30.0(25.0–41.5) 28.0(23.0–33.0) 0.839
 Urea nitrogen, umol/L 2.7(2.3–4.9) 2.9(2.2–4.0) 0.429
 Serum sodium, mmol/L 138.2(135.1–138.2) 136.9(134.0–139.0) 0.880
 Potassium, mmol/L 4.0(3.7–4.1) 4.1(3.7–4.5) 0.396
  1. The data are presented as the median with the 25th and 75th percentiles in square brackets for continuous variables and as n/% for qualitative data as appropriate