|
Fatiguea, b
|
PRO-CTCAE Symptom Term: Fatigue
|
|
Fevera
|
Center specific diagnostic and treatment guidelines based on Petersdorf et al. [34]
|
|
Bleedinga, b
|
Modified WHO Bleeding Scale [13]
|
|
Dyspneaa, b
|
PRO-CTCAE Symptom Term: Shortness of breath
|
|
Paina
|
According to PRO-CTCAE Symptom Term: General pain
|
|
Mooda, b
|
According to PRO-CTCAE Symptom Term: Sad; and based on an instrument by Whooley et al. [35]
|
|
Concentration/memorya, b
|
Combination of PRO-CTCAE Symptom Term: Concentration and PRO-CTCAE Symptom Term: Memory
|
|
Palpitationsa, b
|
PRO-CTCAE Symptom Term: Heart palpitations
|
|
Gastro-intestinal problemsb
|
PRO-CTCAE Symptom Terms: Nausea, Vomiting, Heartburn, Gas, Bloating, Constipation and Diarrhea
|
|
Open question on other symptom
|
N/A
|
|
Items only for AA questionnaire
|
|
Palpitationsa
|
PRO-CTCAE Symptom Term: Heart palpitations
|
|
Tremora
|
According to CTCAE V5.0 Term: Tremor and adopted to PRO-CTCAE style
|
|
Muscle crampsa, b
|
According to CTCAE V5.0 Term: Muscle cramp and adopted to PRO-CTCAE style.
|
|
Paresthesia, numbnessa
|
PRO-CTCAE Symptom Term: Numbness & tingling
|
|
Trouble doing strenuous activitiesb
|
EORTC-QLQ-C30
|
|
Dizzinessb
|
PRO-CTCAE Symptom Term: Dizziness
|
|
Items only for PNH questionnaire
|
|
Hemoglobinuriaa, b
|
N/A
|
|
Jaundicea
|
N/A
|
|
Dysphagiaa, b
|
According to CTCAE V5.0 Term: Dysphagia and adopted to the PRO-CTCAE Symptom Term: Difficulty swallowing
|
|
Erectile dysfunctiona
|
PRO-CTCAE Symptom Term: Achieve and maintain erection
|
|
Itchingb
|
PRO-CTCAE Symptom Term: Itching
|
|
Painb
|
According to PRO-CTCAE Symptom Term: General pain
|
