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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Development of a patient-reported outcome questionnaire for aplastic anemia and paroxysmal nocturnal hemoglobinuria (PRO-AA/PNH)

Fig. 2

Patient-reported outcomes (PRO) in AA, PNH and AA-PNH in the literature. a Comparison of the frequency distribution of symptoms in observational studies and RCT between AA, PNH and AA-PNH. b Comparison of the frequency distribution of symptoms in case reports/series between AA, PNH and AA-PNH. Displayed are only the five most frequently reported symptoms of each disease. *WHO bleeding grade 1–2

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172