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Table 5 Demographic and clinical characteristics of study cohorts after matching

From: Medical costs of Alpha-1 antitrypsin deficiency-associated COPD in the United States

 

AATD-COPD COHORT (CASES)

NON-AATD-COPD COHORT (CONTROLS)

N = 953

N = 7,928

No. of patients

(Column %) / [median]

No. of patients

(Column %) / [median]

Age, mean (SD)

56.24 (10.74)

[56]

55.17 (9.62)

[56]

Age categories, n (%)

 30 - 39

57

(6)

445

(6)

 40 - 49

191

(20)

1,697

(20)

 50 - 59

355

(37)

3,194

(37)

 60 - 64

174

(18)

1,537

(18)

 >=65

176

(18)

1,055

(18)

Gender, n (%)

 Male

456

(48)

3,812

(48)

 Female

497

(52)

4,116

(52)

Race/Ethnicity a , n (%)

 White

877

(92)

7,526

(95)

 African American

39

(4)

201

(3)

 Hispanic

33

(3)

195

(2)

Census region, n (%)

 Northeast

104

(11)

104

(11)

 Midwest

287

(30)

287

(30)

 South

414

(43)

414

(43)

 West

148

(16)

148

(16)

Charlson Comorbidity Score a , n (%)

 1

596

(63)

5,416

(68)

 2

161

(17)

1,282

(16)

 3

90

(9)

592

(7)

 4

40

(4)

207

(3)

  ≥5

66

(7)

431

(5)

  1. aMissing race/ethnicity was replaced using multinomial logistic regression
  2. bQuan's Enhanced Charlson Comorbidity Score calculated within 365 days before (including) the index date