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Table 2 Timing between AATD and COPD diagnoses stratified by time period

From: Medical costs of Alpha-1 antitrypsin deficiency-associated COPD in the United States

AATD-associated COPD subgroup

AATD-COPD Cohort

N = 953

Mean difference (years)

SD

Median

Range

AATD diagnosis before COPD diagnosis (N = 114; 12%)a

 2000 - 2009

1.17

1.12

0.9

4.27

 2010 - 2017

1.77

1.87

1.33

9.75

AATD diagnosis after COPD diagnosis (N = 802; 84%)a

 2000 - 2009

5.42

3.82

4.84

17.38

 2010 - 2017

2.39

1.8

1.62

7.67

  1. atime horizons represent the date of the first COPD diagnosis