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Table 1 Dental and oral findings of STAT3-HIES patients

From: Retained primary teeth in STAT3 hyper-IgE syndrome: early intervention in childhood is essential

ID Age
[years]
Gender retained primary teeth extracted primary teeth (No.) delayed resorption of primary teeth (as to X-ray) oral candidiasis gingivitis aphthous ulcers abnormal dental anatomy other findings Heterozygous STAT3 mutation
#1 37 female no no no yes no no no no c.1144C > T; p.R382W
#2 5 male N/A N/A no X-ray available no no no no median rhomboid glossitis c.1144C > T; p.R382W
#3 17 male yes yes (18) yes yes no yes no no c.1145G > A; p.R382Q
#4 12 female yes yes (20) yes yes no no yes agenesis of
2 premolars
c.1909G > A; p.V637M
#5 32 male no no no no yes no no no c.1152 T > A; p.F348L
#6 16 female yes yes (20) yes no no no no no c.1145G > A; p.R382Q
#7 19 female yes yes (7) yes no no no yes abnormal shaped premolar c.2114 A > C; p.Y705C
#8 23 female yes yes [4] yes no no yes no no c.1406A > G; p.Q469R
#9 24 female yes yes (20) yes yes yes no no no c.1145G > A; p.R382Q
#10 7 male yes yes (2) no X-ray available no yes no no no c.1145G > A; p.R382Q
#11 9 male yes yes (5) yes yes yes no no no c.1145G > A; p.R382Q
#12 8 male yes yes (1) yes yes no no yes agenesis of
1 premolar
c.1144C > T; p.R382W
#13 48 male yes no no X-ray available yes no no no no c.1144C > T; p.R382W
Positive for finding: 83% 75% 80% 54% 31% 15% 15% 8%  
  1. N/A: not applicable