Factor a | Death within 30 days | Death within 7 days | ||
---|---|---|---|---|
OR (95%CI) | p value | OR (95%CI) | p value | |
Age, ≤ 1 year versus > 1 years | 1.77 (0.73, 4.31) | 0.2076 | 3.53 (1.17, 10.67) | 0.0253 |
Admission to PICU | 3.24 (1.59, 6.64) | 0.0013 | 2.49 (0.91, 6.8) | 0.0761 |
Underlying diseases and concomitant diagnosis | ||||
 EBV infection | 0.51 (0.25, 1.02) | 0.0581 | 0.27 (0.09, 0.81) | 0.0191 |
 Sepsis | 5.37 (2.21, 13.05) | 0.0002 | 13.17 (1.71, 101.72) | 0.0134 |
 Other infections | 0.36 (0.15, 0.88) | 0.0254 | 0.13 (0.02, 1.02) | 0.0518 |
 Myocardial damage | 11.76 (5.18, 26.68) | < 0.0001 | 19.05 (4.19, 86.53) | 0.0001 |
 Heart failure | 6.3 (2.61, 15.18) | < 0.0001 | 4.88 (1.72, 13.85) | 0.0029 |
 Shock | 9.97 (3.36, 29.61) | < 0.0001 | 16.5 (5.33, 51.09) | < 0.0001 |
 CNS disease | 5.75 (2.62, 12.6) | < 0.0001 | 3.73 (1.36, 10.23) | 0.0104 |
 Hepatic dysfunction | 8.51 (3.12, 23.18) | < 0.0001 | - b | 0.9346 |
 Severe pneumonia | 11.95 (5.21, 27.44) | < 0.0001 | 5.09 (1.71, 15.12) | 0.0034 |
 Respiratory failure | 14.98 (6.21, 36.15) | < 0.0001 | 15.66 (3.46, 70.9) | 0.0004 |
 ARDS | 9.72 (2.53, 37.3) | 0.0009 | 4.22 (1.15, 15.5) | 0.0299 |
 Coagulopathy | 14.51 (5.29, 39.75) | < 0.0001 | – | 0.9272 |
 DIC | 6.85 (3.12, 15.03) | < 0.0001 | 7.47 (2.59, 21.54) | 0.0002 |
 Acute kidney injury | 7.2 (2.37, 21.92) | 0.0005 | 8.34 (2.65, 26.2) | 0.0003 |
 Gastrointestinal disorder | 12.5 (4.96, 31.47) | < 0.0001 | 4.14 (1.48, 11.61) | 0.0069 |
 MODS | 17.58 (5.87, 52.71) | < 0.0001 | - b | 0.9275 |
 Immunodeficiency | 3.52 (1.62, 7.64) | 0.0015 | 1.79 (0.62, 5.16) | 0.2805 |
HLH therapies | ||||
 Etoposide | 0.1 (0.05, 0.23) | < 0.0001 | 0.02 (0, 0.17) | 0.0002 |
 Cyclosporine A | 0.31 (0.15, 0.67) | 0.0026 | 0.26 (0.1, 0.71) | 0.0089 |
 Dexamethasone | 0.3 (0.13, 0.68) | 0.0041 | 0.16 (0.06, 0.45) | 0.0005 |